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Public Lecture
Public Lecture with Dr. David Julius
December 4, 2017
7:30 PM

From Peppermints to Pit Vipers

With 2017 Canada Gairdner International Award laureate Dr. David Julius

Our senses enable us to interpret and experience the world in which we live. Sensory systems are fine-tuned by evolution to detect signals that are most relevant to an animal’s lifestyle and environment. How do spices and snakes help us understand this important sensory process while generating new ideas for basic research and drug development?

Location: Ontario Science Centre

Presented by TELUS Health in partnership with the Gairdner Foundation.

Tickets on sale now: http://bit.ly/GreatConvos

 

For more information, please visit The Ontario Science Centre page.




Event Information

december, 2017

december, 2017

20174dec7:30 pmPublic Lecture with Dr. David Julius7:30 pm Ontario Science Centre, 770 Don Mills RdEvent Type:Public Lecture

Event Details

From Peppermints to Pit Vipers

With 2017 Canada Gairdner International Award laureate Dr. David Julius

Our senses enable us to interpret and experience the world in which we live. Sensory systems are fine-tuned by evolution to detect signals that are most relevant to an animal’s lifestyle and environment. How do spices and snakes help us understand this important sensory process while generating new ideas for basic research and drug development?

Location: Ontario Science Centre

Presented by TELUS Health in partnership with the Gairdner Foundation.

Tickets on sale now: http://bit.ly/GreatConvos

 

For more information, please visit The Ontario Science Centre page.

Time

(Monday) 7:30 pm

Location

Ontario Science Centre

770 Don Mills Rd

Organizer

Gairdner Foundation, Ontario Science Centre and TELUS Health

Speakers for this event

  • Dr. David Julius

    Dr. David Julius

    Professor & Chair, Department of Physiology; Morris Herzstein Chair in Molecular Biology and Medicine, University of California San Francisco, San Francisco, CA, USA

    The Work: Dr. Julius has used distinctive molecules from the natural world – including toxins from tarantulas and coral snakes, and capsaicin, the molecule that produces the “heat” in chili peppers – to understand how signals responsible for temperature and pain sensation are transmitted by neural circuits to the brain. In his research Dr. Julius has homed in on a class of proteins called TRP (pronounced “trip”) ion channels to discover how the chemical compound responsible for the spicy heat of chili peppers – called capsaicin – elicits a burning sensation when eaten or touched. The research led to the identification and cloning of the specific protein responsible, named TRPV1. On the flip side, Dr. Julius has used menthol, a natural cooling agent, to identify a receptor for “real” cold. This protein, named TRPM8, is a close molecular cousin of TRPV1, pointing to a common mechanism for sensing temperature. As in the case of TRPV1, this ion channel contributes to hypersensitivity to cold, such as that experienced after chemotherapy or other types of nerve injury. The Impact: Somatosensation, our sense of touch and pain, serves as a warning system to guard us against injury. While critical to our survival and well-being, this system can become hypersensitive, resulting in chronic pain. This work helps to explain how such positive and negative aspects of pain sensation arise – insight that is critical to understanding the genesis of chronic pain syndromes. One indication of the importance of this work to medicine is the interest in TRP channels as potential targets for a new generation of painkillers.

    Professor & Chair, Department of Physiology; Morris Herzstein Chair in Molecular Biology and Medicine, University of California San Francisco, San Francisco, CA, USA

20174dec7:30 pmPublic Lecture with Dr. David Julius7:30 pm Ontario Science Centre, 770 Don Mills RdEvent Type:Public Lecture

Event Details

From Peppermints to Pit Vipers

With 2017 Canada Gairdner International Award laureate Dr. David Julius

Our senses enable us to interpret and experience the world in which we live. Sensory systems are fine-tuned by evolution to detect signals that are most relevant to an animal’s lifestyle and environment. How do spices and snakes help us understand this important sensory process while generating new ideas for basic research and drug development?

Location: Ontario Science Centre

Presented by TELUS Health in partnership with the Gairdner Foundation.

Tickets on sale now: http://bit.ly/GreatConvos

 

For more information, please visit The Ontario Science Centre page.

Time

(Monday) 7:30 pm

Location

Ontario Science Centre

770 Don Mills Rd

Organizer

Gairdner Foundation, Ontario Science Centre and TELUS Health

Speakers for this event

  • Dr. David Julius

    Dr. David Julius

    Professor & Chair, Department of Physiology; Morris Herzstein Chair in Molecular Biology and Medicine, University of California San Francisco, San Francisco, CA, USA

    The Work: Dr. Julius has used distinctive molecules from the natural world – including toxins from tarantulas and coral snakes, and capsaicin, the molecule that produces the “heat” in chili peppers – to understand how signals responsible for temperature and pain sensation are transmitted by neural circuits to the brain. In his research Dr. Julius has homed in on a class of proteins called TRP (pronounced “trip”) ion channels to discover how the chemical compound responsible for the spicy heat of chili peppers – called capsaicin – elicits a burning sensation when eaten or touched. The research led to the identification and cloning of the specific protein responsible, named TRPV1. On the flip side, Dr. Julius has used menthol, a natural cooling agent, to identify a receptor for “real” cold. This protein, named TRPM8, is a close molecular cousin of TRPV1, pointing to a common mechanism for sensing temperature. As in the case of TRPV1, this ion channel contributes to hypersensitivity to cold, such as that experienced after chemotherapy or other types of nerve injury. The Impact: Somatosensation, our sense of touch and pain, serves as a warning system to guard us against injury. While critical to our survival and well-being, this system can become hypersensitive, resulting in chronic pain. This work helps to explain how such positive and negative aspects of pain sensation arise – insight that is critical to understanding the genesis of chronic pain syndromes. One indication of the importance of this work to medicine is the interest in TRP channels as potential targets for a new generation of painkillers.

    Professor & Chair, Department of Physiology; Morris Herzstein Chair in Molecular Biology and Medicine, University of California San Francisco, San Francisco, CA, USA




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